Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries

2021-06-25T17:46:45+00:00June 9th, 2020|Comments Off on Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries

CRISPR-mediated Mutation Correction of Hematopoietic Stem Cells from Patients with X-linked Chronic Granulomatous Disease Using Non-Viral Cell Engineering

2020-07-07T16:05:23+00:00May 16th, 2020|Comments Off on CRISPR-mediated Mutation Correction of Hematopoietic Stem Cells from Patients with X-linked Chronic Granulomatous Disease Using Non-Viral Cell Engineering

CRISPR-Cas9 Gene Repair of Hematopoietic Stem Cells From Patients With X-linked Chronic Granulomatous Disease

2020-11-04T21:30:46+00:00June 1st, 2017|Comments Off on CRISPR-Cas9 Gene Repair of Hematopoietic Stem Cells From Patients With X-linked Chronic Granulomatous Disease

Efficient mRNA-based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-induced ADCC against Lymphoma and Targets NK cell Migration Towards the Lymph Node Associated Chemokine CCL19

2020-11-04T21:33:12+00:00March 22nd, 2016|Comments Off on Efficient mRNA-based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-induced ADCC against Lymphoma and Targets NK cell Migration Towards the Lymph Node Associated Chemokine CCL19

Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease

2020-11-04T21:44:35+00:00March 7th, 2016|Comments Off on Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease

Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma

2020-11-04T21:49:02+00:00June 1st, 2015|Comments Off on Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma
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