CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication

2021-06-25T17:18:44+00:00February 11th, 2021|Comments Off on CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication

CRISPR-mediated Mutation Correction of Hematopoietic Stem Cells from Patients with X-linked Chronic Granulomatous Disease Using Non-Viral Cell Engineering

2020-07-07T16:05:23+00:00May 16th, 2020|Comments Off on CRISPR-mediated Mutation Correction of Hematopoietic Stem Cells from Patients with X-linked Chronic Granulomatous Disease Using Non-Viral Cell Engineering

Disruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with b-Thalassemia Major

Patients with severe β-globin thalassemias require life-long red blood cell transfusions along with iron chelation treatment. The only curative option is allogeneic hematopoietic cell transplantation, available only to a subset of patients having a suitable donor.

2020-11-02T22:20:36+00:00August 13th, 2018|Comments Off on Disruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with b-Thalassemia Major

CRISPR-Cas9 Gene Repair of Hematopoietic Stem Cells From Patients With X-linked Chronic Granulomatous Disease

2020-11-04T21:30:46+00:00June 1st, 2017|Comments Off on CRISPR-Cas9 Gene Repair of Hematopoietic Stem Cells From Patients With X-linked Chronic Granulomatous Disease
Go to Top