Electroporation Applications

Electroporation has evolved significantly over the years. Alternative methods were often limited by low efficiency or poor cell viability, but MaxCyte’s advanced electroporation platform overcomes these challenges. Our proprietary technology enables high-performance transfection across a variety of applications, from complex gene editing to large-scale transient protein production.

Research applications

Electroporation is more than just a transfection method—it’s a cornerstone of modern biotechnology and molecular biology. Its ability to deliver therapeutic molecules, genetic material and small compounds into cells makes it indispensable for developing gene-edited cell therapies, producing monoclonal antibodies and biologics and exploring novel drug targets in preclinical research, among other applications. Learn how electroporation can support your specific research area below.

Cell Therapy

Engineer cells at scale to enable safe and potent cell therapies.

Viral Vector Production

Transfect adherent or suspension cells to produce a variety of viral vectors.

Cell Based Assays

Produce assay-ready cells faster with scalable electroporation.

Gene Editing

Navigate the complexities of genome engineering with highly efficient delivery.

Antibody & Protein Production

Accelerate biotherapeutic development with transient expression for gram-scale protein production.

Vaccines

Innovate vaccine research with our adaptable platform for production of recombinant proteins, virus-like particles and more.

Challenges in electroporation & how MaxCyte® solves them

Transfecting difficult cell types

Primary cells, stem cells and certain immune cells are notoriously hard to transfect with traditional methods. MaxCyte’s platform delivers superior results, ensuring high viability and efficiency even for challenging cell types.

Scaling up from R&D to manufacturing

Many electroporation platforms fail to scale effectively for clinical and commercial applications. MaxCyte’s scalability allows seamless transitions across research, preclinical and manufacturing workflows.

Regulatory requirements for cell therapies

Navigating compliance for cell and gene therapies can be daunting. MaxCyte’s technology is GMP-compliant and supported by a history of regulatory approvals, ensuring smooth product development and commercialization.

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Electroporation in emerging fields

Stay ahead in research and development with electroporation applications tailored to cutting-edge industries:

  • Synthetic biology: Deliver plasmids and genetic constructs into cells for creating engineered organisms.
  • mRNA therapeutics: High-efficiency delivery of mRNA for vaccine development and therapeutic applications.
  • Functional genomics: Accelerate gene knockout or knockin studies with precise CRISPR delivery.

Featured resources

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Application Note
CRISPR Electroporation of T Cells Improves Treatment in Patients with Refractory Cancer
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Application Note
MaxCyte® Enables a cGMP-Compatible Manufacturing Process for Highly Efficient T Cell Engineering
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Poster
MaxCyte®: A Versatile Tool for SARS-CoV-2 Response
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