The BioProcess International Conference at Biotech Week, is the premier event for accelerating success in biologics, cell, and gene therapies. Access cutting-edge science, innovative technologies, and industry contacts to enhance efficiencies in biopharmaceutical development and production.
Come visit us at booth #934 and discover MaxCyte’s cGMP-compliant non-viral cell engineering platform and how it enables the acceleration of therapeutic development from concept to clinic.
While at the meeting, don't miss our featured talk:
Streamlining Therapeutic Development with Scalable Electroporation
Date: September 20, 2023
Time: 2:30PM - 3:00PM
Location: Room 205C
Presenter: Joseph Abad, Senior Director, Process Development and Innovation at MaxCyte
The need for the rapid generation of biologics to enable future pandemic preparedness and to support shortened timelines to pre-clinical and early clinical studies continues to grow. Conventional approaches to therapeutic development are far from optimal, often relying on stable cell lines or inadequate transient expression technologies.
In spite of process improvements, stable cell line development remains a lengthy, expensive process not suited to an agile response. Transient gene expression is a promising alternative to stable cell line development, offering the potential to generate protein within a few weeks instead of the months needed for transfection followed by rounds of isolation, screening and expansion. However, traditional transfection methods may be incompatible with relevant cell types, lack scalability and fail to produce the quantity or quality of material required.
To address these challenges, we have developed an efficient, flexible and seamlessly scalable system based on Flow ElectroporationTM. MaxCyte’s technology can expedite the development and manufacturing of biotherapeutics, including monoclonal antibodies, antigens and vaccines, in a range of biomanufacturing cell types. Here we will present a closed system workflow capable of producing multi-gram quantities of protein by transient gene expression in 3-4 weeks from seed train to harvest.