CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication

2021-06-25T17:18:44+00:00February 11th, 2021|Comments Off on CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication

Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones

2021-06-25T17:05:46+00:00November 11th, 2020|Comments Off on Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones

Generating therapeutic monoclonal antibodies to complex multi-spanning membrane targets: Overcoming the antigen challenge and enabling discovery strategies

2021-03-24T15:14:01+00:00November 2nd, 2020|Comments Off on Generating therapeutic monoclonal antibodies to complex multi-spanning membrane targets: Overcoming the antigen challenge and enabling discovery strategies

Effectual Labeling of Natural Killer Cells with Upconverting Nanoparticles by Electroporation for In Vivo Tracking and Biodistribution Assessment

2021-06-25T17:30:18+00:00October 13th, 2020|Comments Off on Effectual Labeling of Natural Killer Cells with Upconverting Nanoparticles by Electroporation for In Vivo Tracking and Biodistribution Assessment

Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity

2021-06-25T17:48:27+00:00July 4th, 2020|Comments Off on Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity

Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries

2021-06-25T17:46:45+00:00June 9th, 2020|Comments Off on Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries

Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens

2020-11-04T22:29:57+00:00May 29th, 2020|Comments Off on Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens
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