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Development of a genome-wide CRISPR screen in CD4+ T cells to identify drug targets for immune-mediated inflammatory diseases

2021-04-13T17:39:43+00:00April 12th, 2021|Comments Off on Development of a genome-wide CRISPR screen in CD4+ T cells to identify drug targets for immune-mediated inflammatory diseases

CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication

2021-06-25T17:18:44+00:00February 11th, 2021|Comments Off on CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication

Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones

2021-06-25T17:05:46+00:00November 11th, 2020|Comments Off on Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones

Generating therapeutic monoclonal antibodies to complex multi-spanning membrane targets: Overcoming the antigen challenge and enabling discovery strategies

2021-03-24T15:14:01+00:00November 2nd, 2020|Comments Off on Generating therapeutic monoclonal antibodies to complex multi-spanning membrane targets: Overcoming the antigen challenge and enabling discovery strategies

Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform

2021-03-24T15:37:30+00:00November 2nd, 2020|Comments Off on Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform

Effectual Labeling of Natural Killer Cells with Upconverting Nanoparticles by Electroporation for In Vivo Tracking and Biodistribution Assessment

2021-06-25T17:30:18+00:00October 13th, 2020|Comments Off on Effectual Labeling of Natural Killer Cells with Upconverting Nanoparticles by Electroporation for In Vivo Tracking and Biodistribution Assessment
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