Amplicon-seq™

Confirmation Assay

SeQure Dx's Amplicon-seq assay provides high-sensitivity confirmation of on- and off-target edits in gene-edited cell lines and tissues. Targeted amplicon sequencing is guided by the results of ONE-seq, DEUX-seq, and GUIDE-seq, enabling precise validation of gene editing outcomes in your cells of interest. By delivering detailed and accurate editing confirmation, Amplicon-seq supports regulatory expectations, reduces risks of IND filing delays, and strengthens the safety profile of your cell and gene therapy development programs.

Amplicon-seq Overview

SDX-Amplicon-seq Overview

Amplicon-seq

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High sensitivity confirmation of off-targets in your cell type of interest post-editing. Informed by our nomination assays, we know exactly where we need to look to confirm editing.

Confirmation

Verifies cellular edits

  • Sensitive detection methods
  • Relevant cell types
  • On- and off-target analysis

Cellular Editing Assessment

IND Filings

  • Biologic impact assessment
  • GLP

Featured Resources

SDX-Amplicon report
Example report
Amplicon-seq Confirmation Assay Example Report
SDX-SAFER Detection for Efficient Interrogation of DNA Rearrangements in Gene-Edited Human Cells-Figure 2D
Poster
SAFER Detection for efficient Interrogation of DNA Rearrangements in Gene-edited Human Cells
SDX-Safer detection report
Example Report
SAFER Detection Confirmation Assay Example Report
View All Resources
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Related Confirmation Assays

SAFER Detection

High sensitivity confirmation of structural rearrangements in your cell type of interest post-editing. NGS interrogation allows for resolution down to exact genomic coordinates. 

Discover a comprehensive suite of assays spanning from early discovery through pre-clinical and clinical development.

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