DEUX-seq™
Nomination assay
SeQure's DEUX-seq is a biochemical, orthogonal nomination assay that validates and reinforces ONE-seq findings to support regulatory requirements. DEUX-seq leverages in vitro cutting of genomic DNA followed by deep sequencing to determine potential off-target effects with your gene editing tool of interest.
DEUX-seq overview
DEUX-seq
Orthogonal approach to supplement ONE-seq off-target nomination. Unbiased, biochemical, off-target editing assay provides a complementary approach to supplement your off-target risk assessment efforts.
Nomination
Comprehensive off-target assessment
- Highly sensitive
- Universal for all editors
- Population-scale variant assessment
Off-target assessment
IND filings
Guide RNA selection
- Multiple orthogonal methods
- Variant effect prediction
- GLP
Related nomination assays
Learn more about our comprehensive suite of assays spanning from early discovery through pre-clinical and clinical development.
