DEUX-seq™
Nomination Assay
SeQure Dx's DEUX-seq is a biochemical, orthogonal nomination assay that validates and reinforces ONE-seq findings to support regulatory requirements. DEUX-seq leverages in vitro cutting of genomic DNA followed by deep sequencing to determine potential off-target effects with your gene editing tool of interest.
DEUX-seq Overview
DEUX-seq
Orthogonal approach to supplement ONE-seq off-target nomination. Unbiased, biochemical off-target editing assay provides a complementary approach to supplement your off-target risk assessment efforts.
Nomination
Comprehensive off-target assessment
- Highly sensitive
- Universal for all editors
- Population-scale variant assessment
Off-Target Assessment
IND Filings
Guide RNA Selection
- Multiple orthogonal methods
- Variant effect prediction
- GLP
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